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Propolis is a mixture of some secretions from bees and resins from plants. To protect the hive and its nutritious contents from attack by micro-organisms, propolis has anti-microbial properties. Propolis is composed of chemicals (especially flavonoids), which play a role as antiviral and antibacterial agents.

Laboratory tests have demonstrated that propolis is effective against over 20 kinds of bacteria. Clinical studies also demonstrated that propolis was effective against various kinds of bacterial, fungal, and viral infections. According to recent study, active ingredients in propolis significantly inhibited flu virus also.

As it is getting more strict in using antibiotics globally, people are highly concerned about organic food and meat. Samjo Life Science goal is to produce a variety of feed additives contain propolis (phytonutrient) and to supply those for our customers.

According to recently report Phytotherapy Research in 2010, a substance in propolis was active against MRSA, which causes potentially fatal infection. They tested extracts of propolis on 15 MRSA strains and isolated two compounds, Propolin C and Propolin D, which showed good activity against all the MRSA strains tested. These could possibly act as templates for the development of improved anti-MRSA agents.

Natural antibiotics
Natural antioxidants
Substance Properties Reference
caffeic acid
(3,4-dihydroxycinnamic acid)
Antibacterial effect
Antiviral Effect
Cure for imflammation
Villanuevaet et al., 1970
Bankova et al., 1983
Antiviral Effect
Cure for ulcers
Konig and Dustmann, 1985
The hive and the honey
bee, 1992
P-coumaric acid
(4-hydroxycinnamic acid)
Antibacterial effect Metzner et al., 1979
Bacillus penicillin tetracycline Monmycin Propolis
+ ++ - +++
+ + + +++
+ ++ - ++
+ + + +++
Test period : January 25, 2006 ~ February 25, (30 days)
Test farm : W farm in Changnyung, Kyungnam
Test dose : Propolis added to feed for lactation piglets 300g per 1 ton feed

Result :
Weaned pig Weaned pig Wt.(kg) No. of Weak pig No. of survived pigs from weak pigs Mortality rate(%)
Control group 340 6.8 20 15 25
Test group 374 7.5 20 19 5

Conclusion :
After adding the Propolis to the feed of lactating pigs, the vitality of the 10day-pilglets’ in the test group was better than those of the control group and the recovery rate appeared higher.
The test group’s mortality rate (5%) was considerably lower than the control group’s mortality rate(25%).
Test period : January 25, 2006 ~ February 25, (30 days)
Test farm : B farm in Pocheon, Kyungki-do
Control group : General antibiotics, probiotics
Test group : Add propolis product

Result 1 :
Weaned pig Survived pig Mortality rate
Control group 320 308 3.75%
Test group 320 315 1.56%

Result 2 :
Weaned pig Weaned pig Wt.(kg) Final Wt.(kg) Gained Wt.(kg)
Control group 21 6.4 17.0 10.6
Test group 19 6.2 17.6 11.4

Conclusion :
1. In the test group, mortality rate appeared only 1.56% compared to the control group (3.75%).
2. Gained weight in the test group is 7.55% higher more than the control group.