In many species the first visible signs of biotin deficiency appear in the epidermal tissues. In poultry, poor feathering, foot lesions, leg weakness and deformity. In growing pigs, both growth rate and food utilization are adversely affected. In breeding sows, a deficiency of biotin can adversely influence reproductive performance and there is some evidence that biotin deficiency may induce hoof cracks and sole erosion in ruminants.
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